On the performance of proton-transfer-reaction mass spectrometry for breath-relevant gas matrices

• Published in: Measurement science & technology Vol. 24; no. 12; pp. 1 - 13
• Main Authors: Beauchamp, J, Herbig, J, Dunkl, J, Singer, W, Hansel, A
• Format: Journal Article
• Language: English
• Published: IOP Publishing 01.12.2013
• Subjects: Calibration; Carbon dioxide; gas calibration unit; limit of detection; Mass spectrometry; Mathematical analysis; Matrices (mathematics); proton-transfer-reaction mass spectrometry; Relative humidity; Volatile organic compounds

The accuracy of quantitative volatile organic compound (VOC) detection by proton-transfer-reaction mass spectrometry (PTR-MS) is substantially enhanced if the instrument is calibrated. Although quantification of a compound is in principle possible by mathematical methods based on kinetic theory, the...