Dual-functionalization based on combination of quercetin compound and rare earth nanoparticle

While the nanoparticles like La2O3 and other rare earth oxides were believed to be able to provide effective scavenging hydroxyl radical. Quercetin, a hydrophobic agent, showed some potential antibacterial activity. The present work successfully performed the surface modification of rare earth nanop...

Full description

Saved in:
Bibliographic Details
Published inJournal of rare earths Vol. 31; no. 7; pp. 709 - 714
Main Author 王坤杰 吴龚平 李红霞 李明亮 张德懿 冯辉霞 范海燕
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.07.2013
Subjects
antibacterial
Antiinfectives and antibacterials
Hydroxyl radicals
modification
Nanocomposites
Nanomaterials
Nanostructure
quercetin
Rare earth compounds
Rare earth metals
rare earth nanoparticle
Scanning electron microscopy
Scavenging
scavenging hydroxyl radical
Surface chemistry
化合物
基础
官能化
扫描电子显微镜
槲皮素
稀土氧化物
纳米粒子
羟基自由基
quercetin
antibacterial
scavenging hydroxyl radical
modification
rare earth nanoparticle
Online AccessGet full text

Cover

More Information
Summary:While the nanoparticles like La2O3 and other rare earth oxides were believed to be able to provide effective scavenging hydroxyl radical. Quercetin, a hydrophobic agent, showed some potential antibacterial activity. The present work successfully performed the surface modification of rare earth nanoparticle using facile and general strategy. In specific, the hydrophobic quercetin was grafted on the rare earth nanoparticle through the coupling with silane. The surface modified nanoparticle was characterized by Fourier-transform infrared （FTIR）, thermogravimetric analysis （TGA）, and scanning electron microscopy （SEM）. The surface modification helped to retain both the scavenging hydroxyl radical property of rare earth nanoparticle and the antibacterial activity of quercetin. This dual-function properties showed potential for application in the development of biomedicine such as antioxidant, anti-inflammatory, antibacterial and anticancer.
Bibliography:rare earth nanoparticle; quercetin; modification; scavenging; hydroxyl radical; antibacterial
11-2788/TF
While the nanoparticles like La2O3 and other rare earth oxides were believed to be able to provide effective scavenging hydroxyl radical. Quercetin, a hydrophobic agent, showed some potential antibacterial activity. The present work successfully performed the surface modification of rare earth nanoparticle using facile and general strategy. In specific, the hydrophobic quercetin was grafted on the rare earth nanoparticle through the coupling with silane. The surface modified nanoparticle was characterized by Fourier-transform infrared （FTIR）, thermogravimetric analysis （TGA）, and scanning electron microscopy （SEM）. The surface modification helped to retain both the scavenging hydroxyl radical property of rare earth nanoparticle and the antibacterial activity of quercetin. This dual-function properties showed potential for application in the development of biomedicine such as antioxidant, anti-inflammatory, antibacterial and anticancer.
WANG Kunjie, WU Yanping , LI Hongxia , LI Mingliang,ZHANG Deyi, FENG Huixia, FAN Haiyan （1. College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou 730050, China; 2. Chemistry Department, Claflin University, Orangeburg,SC 29115, United States）
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ISSN:1002-0721
2509-4963
DOI:10.1016/S1002-0721(12)60346-9