Recent advances in the syntheses, transformations and applications of 1,1-dihalocyclopropanes
gem -Dihalocyclopropanes have wide-spread applications in organic synthesis due to their versatile chemistry. They can serve as substrates for a large range of useful materials such as natural products, alkaloids, cyclopropanes, heterocycles, aromatic ring systems etc . Normally the dihalocyclopropa...
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| Published in | Organic & biomolecular chemistry Vol. 13; no. 33; pp. 878 - 882 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
01.01.2015
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| Online Access | Get full text |
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| Summary: | gem
-Dihalocyclopropanes have wide-spread applications in organic synthesis due to their versatile chemistry. They can serve as substrates for a large range of useful materials such as natural products, alkaloids, cyclopropanes, heterocycles, aromatic ring systems
etc
. Normally the dihalocyclopropanes are prepared by the addition of dihalocarbene to alkene, but due to the great synthetic efficacy of
gem
-dihalocyclopropanes a number of methods have been developed for their synthesis. Generally
gem
-dihalocyclopropanes exist as strained cyclic systems with astonishing kinetic stability. They are capable of undergoing transformations leading to a variety of products which have potential applications in various synthetic organic chemistry fields.
gem
-Dihalocyclopropanes have wide-spread applications in organic synthesis due to their versatile chemistry. The various new methods of synthesis, reactions and applications of these synthetically useful compounds are described. |
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| Bibliography: | K.S. Sindhu was born in Kerala, India, in 1983. She received her B.Sc. degree from Mahatma Gandhi University (St. Xaviers College, Aluva) in 2003 and her M.Sc. degree from School of Chemical Sciences, Mahatma Gandhi University in 2007. She cleared the National Eligibility test (NET) with a scholarship. Currently she is doing her doctoral research under the guidance of Dr G. Anilkumar in the School of Chemical Sciences, Mahatma Gandhi University. K. Keerthi Krishnan was born in 1989 in Kerala, India. She received her B.Sc. and M.Sc. degrees in Chemistry from N.S.S Hindu College, Changanacherry in 2009 and 2011 respectively, B.Ed. degree from N.S.S Training College, Changanacherry in 2012 and M.Phil. (Organic Chemistry) degree from the School of Chemical Sciences, Mahatma Gandhi University in 2013. Currently she is pursuing her doctoral research under the guidance of Dr G. Anilkumar in the School of Chemical Sciences, Mahatma Gandhi University. Amrutha P. Thankachan was born in Kerala, India, in 1988. She obtained her B.Sc. degree from Mahatma Gandhi University (C M S College, Kottayam) in 2009 and her M.Sc. degree from School of Chemical Sciences, Mahatma Gandhi University in 2011. Currently she is doing her doctoral research under the guidance of Dr G. Anilkumar in the School of Chemical Sciences, Mahatma Gandhi University. Gopinathan Anilkumar was born in Kerala, India and obtained his PhD in 1996 from the Regional Research Laboratory, Trivandrum with Dr Vijay Nair. He did postdoctoral studies at the University of Nijmegen, Netherlands (with Professor Binne Zwanenburg), Osaka University, Japan (with Professor Yasuyuki Kita), Temple University, USA (with Professor Franklin Davis) and Leibniz-institüt für Katalyse, Rostock, Germany (with Professor Matthias Beller). He was a senior scientist at AstraZeneca (India). Currently he is Associate Professor in Organic Chemistry at the School of Chemical Sciences, Mahatma Gandhi University in Kerala, India. His research interests are in the areas of organic synthesis, medicinal chemistry and catalysis, particularly on ruthenium, iron, zinc and copper catalyzed reactions. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1477-0520 1477-0539 |
| DOI: | 10.1039/c5ob01088h |