Campylobacter pylori and gastroduodenal ulcer disease. A prospective study in a Swedish population

In a consecutive prospective series of 208 Swedish primary peptic ulcer patients, 146 gastric, 55 duodenal and 7 in both sites, gastroduodenitis was found in 97.6% of the cases. The mucosal inflammation was associated with CP in 87% and 91% of the gastric and duodenal ulcer cases respectively. No si...

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Bibliographic Details
Published inScandinavian journal of gastroenterology. Supplement Vol. 167; p. 81
Main Authors Gad, A, Hradsky, M, Furugård, K, Malmodin, B
Format Journal Article
LanguageEnglish
Published England 1989
Subjects
Adult
Aged
Aged, 80 and over
Aluminum Hydroxide - therapeutic use
Anti-Ulcer Agents - therapeutic use
Bismuth - therapeutic use
Campylobacter Infections - epidemiology
Drug Combinations - therapeutic use
Female
Glycyrrhiza
Histamine H2 Antagonists - therapeutic use
Humans
Magnesium Hydroxide
Male
Middle Aged
Peptic Ulcer - drug therapy
Peptic Ulcer - epidemiology
Peptic Ulcer - etiology
Pilot Projects
Plant Extracts - therapeutic use
Prospective Studies
Sodium Bicarbonate
Sweden - epidemiology
Sweden
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Summary:In a consecutive prospective series of 208 Swedish primary peptic ulcer patients, 146 gastric, 55 duodenal and 7 in both sites, gastroduodenitis was found in 97.6% of the cases. The mucosal inflammation was associated with CP in 87% and 91% of the gastric and duodenal ulcer cases respectively. No significant correlation was found between CP colonisation and the type or severity of mucosal inflammation. Gastric metaplasia was present in only 8% of 48 bulbar ulcer cases. Ulcer healing and eradication of CP was achieved in 52% of patients treated with bismuth subnitrate in combination with erythromycin or according to the triple approach.
ISSN:0085-5928
DOI:10.3109/00365528909091318