Exploiting the temporal patterning of transient VEP signals: A statistical single-trial methodology with implications to brain–computer interfaces (BCIs)

• Published in: Journal of neuroscience methods Vol. 232; pp. 189 - 198
• Main Authors: Liparas, D., Dimitriadis, S.I., Laskaris, N.A., Tzelepi, A., Charalambous, K., Angelis, L.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 30.07.2014
• Subjects: Attention - physiology; BCI; Brain - physiology; Brain Mapping; Brain-Computer Interfaces; Decoding; Discrimination (Psychology); Electroencephalography; Evoked Potentials, Visual - physiology; Female; Functional Laterality; Humans; Mahalanobis-Taguchi system; Male; Photic Stimulation; Transient VEPs; User-Computer Interface; Visual Perception - physiology; BCI; Decoding; Transient VEPs; Mahalanobis-Taguchi system
• ISSN: 0165-0270; 1872-678X; 1872-678X
• DOI: 10.1016/j.jneumeth.2014.04.032

•Single-trial TVEPs encode information about stimulus that can be robustly detected within a well-defined latency-range.•The response is readily enhanced by means of an operator that forms a spatial difference.•Attention modulates the TVEPs in a way that is decodable from the enhanced response by means of a Mahalanobis-Taguchi system. When visual evoked potentials (VEPs) are deployed in brain–computer interfaces (BCIs), the emphasis is put on stimulus design. In the case of transient VEPs (TVEPs) brain responses are never treated individually, i.e. on a single-trial (ST) basis, due to their poor signal quality. Therefore their main characteristic, which is the emergence during early latencies, remains unexplored. Following a pattern-analytic methodology, we investigated the possibility of using single-trial TVEP responses to differentiate between the different spatial locations where a particular visual stimulus appeared and decide whether it was attended or unattended by the subject. Covert spatial attention modulates the temporal patterning of TVEPs in such a way that a brief ST-segment, from a single synthesized sensor, is sufficient for a Mahalanobis-Taguchi (MT) system to decode subject's intention. In contrast to previous VEP-based approaches, stimulus-related information and user's intention are being decoded from transient ST-signals via exploiting aspects of brain response in the temporal domain. We demonstrated that in the TVEP signals there is sufficient discriminative information, coming in the form of a temporal code. We were able to introduce an efficient scheme that can fully exploit this information for the benefit of online classification. The measured performance brings high expectations for incorporating these ideas in BCI-control.