Antiparasitic properties of homoallylamines and related compounds

A study of some antiparasitic properties of several homoallylamines and related tetrahydroquinolines and quinolines, previously described, was carried out using in vitro activity assays against the epimastigote form of Trypanosoma cruzi and against Trichomonas vaginalis. Unspecific cytotoxicity agai...

Full description

Saved in:
Bibliographic Details
Published inActa parasitologica Vol. 51; no. 1; pp. 73 - 78
Main Authors Gómez-Barrio, Alicia, Montero-Pereira, David, Nogal-Ruiz, Juan, Escario, José, Muelas-Serrano, Susana, Kouznetsov, Vladimir, Vargas Méndez, Leonor, Urbina Gonzáles, Juan, Ochoa, Carmen
Format Journal Article
LanguageEnglish
Published Berlin Versita 01.03.2006
Springer Nature B.V
Subjects
antichagasic
Garlic
Homoallylamines
quinolines
tetrahydroquinolines
trichomonacidal
Trichomonas vaginalis
Trypanosoma cruzi
unspecific cytotoxicity
Online AccessGet full text

Cover

More Information
Summary:A study of some antiparasitic properties of several homoallylamines and related tetrahydroquinolines and quinolines, previously described, was carried out using in vitro activity assays against the epimastigote form of Trypanosoma cruzi and against Trichomonas vaginalis. Unspecific cytotoxicity against murine macrophages was also studied. Although the antichagasic and trichomonacidal activities are not comparable to those of the standard drugs, nifurtimox and metronidazole, some of the compounds exhibit an interesting specific antiparasitic activity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1230-2821
1896-1851
DOI:10.2478/s11686-006-0010-z