Growth in adulthood after liver transplantation for glycogen storage disease type I

Continuation of linear growth late into the third decade of life is rarely observed. This report describes a 27-year-old man with delayed growth and sexual maturation secondary to glycogen storage disease type I who grew 5.3 cm after orthotopic liver transplantation. Sequential improvement in select...

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Bibliographic Details
Published inGastroenterology (New York, N.Y. 1943) Vol. 101; no. 1; p. 238
Main Authors Kirschner, B S, Baker, A L, Thorp, F K
Format Journal Article
LanguageEnglish
Published United States 01.07.1991
Subjects
Adult
Anthropometry
Glycogen Storage Disease Type I - metabolism
Glycogen Storage Disease Type I - physiopathology
Glycogen Storage Disease Type I - surgery
Growth
Humans
Liver Transplantation
Male
Sexual Maturation
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Summary:Continuation of linear growth late into the third decade of life is rarely observed. This report describes a 27-year-old man with delayed growth and sexual maturation secondary to glycogen storage disease type I who grew 5.3 cm after orthotopic liver transplantation. Sequential improvement in selected measures of metabolic control (blood glucose, lactate, and bicarbonate concentrations) and growth-promoting peptides (testosterone and insulinlike growth factor I) were documented after transplantation and before the increase in height. Potential increases in final stature may be present in adult patients with underlying metabolic disease and delayed skeletal maturation.
ISSN:0016-5085
DOI:10.1016/0016-5085(91)90483-2