Ocular masquerade syndrome associated with extranodal nasal natural killer/T-cell lymphoma: case report

A 33-year-old woman complained of unilateral eyelid edema and blurred vision. Initial ophthalmic examination disclosed anterior chamber reaction with keratic precipitates on the cornea, without posterior abnormalities. Anterior uveitis was treated. Despite that, patient showed rapidly progressive un...

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Published inArquivos brasileiros de oftalmologia Vol. 75; no. 6; pp. 430 - 432
Main Authors Abe, Ricardo Yuji, Pinto, Roberto Damian Pacheco, Bonfitto, João Felipe Leite, Lira, Rodrigo Pessoa Cavalcanti, Arieta, Carlos Eduardo Leite
Format Journal Article
LanguageEnglish
Published Brazil Conselho Brasileiro de Oftalmologia 01.11.2012
Subjects
Adult
Eye Neoplasms - pathology
Fatal Outcome
Female
Humans
Lymphoma, Extranodal NK-T-Cell - pathology
Magnetic Resonance Imaging
Nose Neoplasms - pathology
OPHTHALMOLOGY
Optic Nerve - pathology
Optic Neuritis - etiology
Syndrome
Uveitis - complications
Vision Disorders - etiology
Immunohistochemistry
Neoplasias nasaisl
Optic neuritis
Humans
Linfoma de células T
Células matadoras naturaisl
Male
Killer cells
Case report
Uveites
Feminino
Nose neoplasms
Uveitis
Lymphoma T-Cell
Adult
Transtornos da visãol
Eye neoplasms
Vision disorders
Humanos
natural
Imunoistoquímica
Relato de caso
Adulto
Neoplasias oculares
Neurite óptica
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Summary:A 33-year-old woman complained of unilateral eyelid edema and blurred vision. Initial ophthalmic examination disclosed anterior chamber reaction with keratic precipitates on the cornea, without posterior abnormalities. Anterior uveitis was treated. Despite that, patient showed rapidly progressive unilateral vision loss with optic nerve swelling. Systemic workup was inconclusive, as well as cranial magnetic resonance imaging and cerebrospinal fluid examination. Based on the hypothesis of optic neuritis, intravenous methylprednisolone pulse was performed with no success. During the following days, the patient presented pericardial effusion and cardiac tamponade, progressing to death. Necropsy was performed and diagnosis of extranodal natural killers/T-cell lymphoma, nasal type with ocular involvement was confirmed by immunohistochemistry.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:0004-2749
1678-2925
1678-2925
DOI:10.1590/S0004-27492012000600013