Basic endocrine products of adipose tissue in states of thyroid dysfunction

Over the past decade it has been established that adipose tissue is capable of secreting a variety of hormones, cytokines, growth factors, and other peptides that are capable of changing adipocyte biology as well as different organ systems, like the central nervous system, liver, pancreas, and skele...

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Bibliographic Details
Published inThyroid (New York, N.Y.) Vol. 17; no. 5; p. 421
Main Authors Pontikides, Nikolaos, Krassas, Gerasimos E
Format Journal Article
LanguageEnglish
Published United States 01.05.2007
Subjects
Adiponectin - physiology
Adipose Tissue - metabolism
Animals
Humans
Hyperthyroidism - metabolism
Hypothyroidism - metabolism
Interleukin-6 - physiology
Resistin - physiology
Thyroid Gland - physiology
Tumor Necrosis Factor-alpha - physiology
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Summary:Over the past decade it has been established that adipose tissue is capable of secreting a variety of hormones, cytokines, growth factors, and other peptides that are capable of changing adipocyte biology as well as different organ systems, like the central nervous system, liver, pancreas, and skeletal muscles. Also, it is well known that changes of thyroid function are associated with marked changes in both body weight and energy expenditure. In recent years an extensive research is under way to explore the mutual roles of different adipokines and thyroid hormones. The aim of this review is to summarize our current knowledge on the role of basic peptides of adipose tissue, such as adiponectin, interleukin-6, tumor necrosis factor-alpha, and resistin, in states of altered thyroid function.
ISSN:1050-7256
DOI:10.1089/thy.2007.0016