Compliance to anti-diabetic drugs: observations from the diabetic clinic of a medical college in kolkata, India

• Published in: Journal of clinical and diagnostic research Vol. 7; no. 4; pp. 661 - 665
• Main Authors: Mukherjee, Shuvankar, Sharmasarkar, Biswanath, Das, Kaushik Kumar, Bhattacharyya, Agnihotri, Deb, Animesh
• Format: Journal Article
• Language: English
• Published: India JCDR Research and Publications (P) Limited 01.04.2013; JCDR Research and Publications Private Limited
• Subjects: anti-diabetic drugs; compliance; Original; type 2 diabetes; Type 2 diabetes; Compliance; Anti-Diabetic drugs
• ISSN: 2249-782X; 0973-709X
• DOI: 10.7860/JCDR/2013/5352.2876

The poor glycaemic control among the patients with type 2 diabetes constitutes a major public health problem and a major risk factor for the development of diabetes complications. To study the compliance rate of the patients with type 2 diabetes to the prescribed medications, to find out its correlation with different socio-demographic factors and other patient characteristics and to find out the reasons behind the non-compliance, if any. This cross sectional study was conducted on the patients with type 2 diabetes, who Attended the Diabetic Clinic of a Medical College in Kolkata, India. The patients of type 2 diabetes who attended the diabetes clinic between April to August 2012 were recruited in the study by systematic random sampling and they were interviewed by using the help of a structured interview schedule. The patients who reported taking less than 80% of their prescribed anti-diabetes medicines in the preceding week and had HbA1C of < 7% were considered to be non-compliant. The data was analyzed by using the SPSS software. The Chi-square test was used to assess the association of the compliance with the different study variables. A binary logistic regression analysis helped in identifying the factors which contributed to the non-compliance. The compliance rate to the anti-diabetic drugs was found to be 57.7%. A univariate analysis showed that it decreased significantly with increasing age and that it was also significantly lower among males, illiterates, those with a poor per capita monthly income and those who had a longer duration of diabetes. It varied significantly with the type of drugs, being lowest with an oral drug and insulin combination (43.4%). No knowledge on the complications of diabetes was significantly associated with a lower compliance. The binary logistic regression also helped in identifying these as the significant contributory factors. The common reasons behind the non-compliance were forgetfulness (44.7%) and financial constraints (32.7%). It can be concluded that the compliance to anti-diabetic drugs was quite poor among the participants. Increasing age, the male sex, illiteracy, a low monthly income and a longer duration of diabetes were significantly associated with the non compliance. A more concerning fact was the significant association of the non-compliance with the types of drug regimens and a lack of knowledge on the complications of diabetes, which emphasized the role of a repeated patient education regarding the basic aspects of diabetes.