Surveillance-Detected Hepatic Metastases From Colorectal Cancer Had a Survival Advantage in Seven-Year Follow-Up

• Published in: Diseases of the colon & rectum Vol. 48; no. 4; pp. 744 - 748
• Main Authors: Child, P W, Yan, T D, Perera, D S, Morris, D L
• Format: Journal Article
• Language: English
• Published: Secaucus, NJ The ASCRS 01.04.2005; Springer; Lippincott Williams & Wilkins Ovid Technologies
• Subjects: Adenocarcinoma - diagnosis; Adenocarcinoma - secondary; Adenocarcinoma - surgery; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Colorectal Neoplasms - pathology; Colorectal Neoplasms - surgery; Female; Follow-Up Studies; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Liver Neoplasms - diagnosis; Liver Neoplasms - secondary; Liver Neoplasms - surgery; Male; Mass Screening; Medical sciences; Middle Aged; Population Surveillance; Retrospective Studies; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Survival Analysis; Tumors; Rectal disease; Prognosis; Colorectal cancer; Hepatic disease; Malignant tumor; Metastasis; Survival; Colonic disease; Carcinoembryonic antigen; Liver cancer; Advantage; Surveillance; Hepatic metastases; Digestive diseases; Intestinal disease
• ISSN: 0012-3706; 1530-0358
• DOI: 10.1007/s10350-004-0852-0

PURPOSE: METHODS: RESULTS:Potentially curative operations were possible in 51.3 percent (79/154) of Group A patients and 28.1 percent (16/57) of Group B patients (P = 0.0043, chi-squared test). In Groups A and B, 24 percent (37/154) and 43.9 percent (25/57) of patients, respectively, were inoperable. The three-year and five-year survival rates after detection of liver metastases were 26.8 percent (41/153) in Group A and 12.5 percent (7/56) in Group B, and 5.9 percent (9/153) in Group A and 8.9 percent (5/56) in Group B, respectively. Log-rank analysis resulted in P = 0.05, Breslow test in P = 0.01. CONCLUSION: