Serotypes not Included in 13-Valent Pneumococcal Vaccine as Causes of Acute Otitis Media with Spontaneous Tympanic Membrane Perforation in a Geographic Area with High Vaccination Coverage

In 177 children living in an area with high 13-valent pneumococcal conjugate vaccine 13 coverage, who had acute otitis media complicated with spontaneous tympanic membrane perforation, Streptococcus pneumoniae was identified in the middle ear fluid of 48 (27.1%) subjects, with 37 (77.1%) cases cause...

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Bibliographic Details
Published inThe Pediatric infectious disease journal Vol. 36; no. 5; p. 521
Main Authors Marchisio, Paola, Esposito, Susanna, Picca, Marina, Baggi, Elena, Terranova, Leonardo, Orenti, Annalisa, Biganzoli, Elia, Principi, Nicola
Format Journal Article
LanguageEnglish
Published United States 01.05.2017
Subjects
Child
Child, Preschool
Exudates and Transudates - microbiology
Female
Humans
Infant
Male
Otitis Media - complications
Otitis Media - microbiology
Pneumococcal Infections - microbiology
Pneumococcal Vaccines - immunology
Serogroup
Streptococcus pneumoniae - classification
Streptococcus pneumoniae - isolation & purification
Tympanic Membrane Perforation - microbiology
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Summary:In 177 children living in an area with high 13-valent pneumococcal conjugate vaccine 13 coverage, who had acute otitis media complicated with spontaneous tympanic membrane perforation, Streptococcus pneumoniae was identified in the middle ear fluid of 48 (27.1%) subjects, with 37 (77.1%) cases caused by nonpneumococcal conjugate vaccine 13 serotypes.
ISSN:1532-0987
DOI:10.1097/INF.0000000000001485