Anti-inflammatory studies on Polygonum glabrum
Anti-inflammatory studies were conducted on a hot water decoction and on an ethanol extract of the stems of Polygonum glabrum. Effective anti-inflammatory activity was demonstrated against acute carrageenan-induced paw oedema, exudate and granuloma formation in the granuloma pouch test, acute and de...
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Published in | Journal of ethnopharmacology Vol. 19; no. 3; pp. 255 - 267 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Ireland
01.05.1987
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Subjects | |
Online Access | Get more information |
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Summary: | Anti-inflammatory studies were conducted on a hot water decoction and on an ethanol extract of the stems of Polygonum glabrum. Effective anti-inflammatory activity was demonstrated against acute carrageenan-induced paw oedema, exudate and granuloma formation in the granuloma pouch test, acute and delayed reactions in formaldehyde arthritis, and acute primary and delayed secondary reactions in adjuvant-induced polyarthritis in albino rats. The acute toxicity in albino mice and 1-month studies on subacute toxicity in rats suggested a good margin of safety. The extract was more effective parenterally than by oral administration. |
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ISSN: | 0378-8741 1872-7573 |
DOI: | 10.1016/0378-8741(87)90003-1 |