In Vitro Anti-oxidant Effect of Vitamin E on Oxidative Stress Induced due to Pesticides in Rat Erythrocytes
An attempt was made to study the antioxidant property of vitamin E in endosulfan and chlorpyrifos toxicity. Erythrocytes were collected from healthy rats and exposed to 1 ppm endosulfan and chlorpyrifos pesticides individually and also along with vitamin E treatment. Results showed that endosulfan w...
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Published in | Toxicology international Vol. 18; no. 1; pp. 73 - 76 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
India
Medknow Publications and Media Pvt. Ltd
01.01.2011
Medknow Publications & Media Pvt. Ltd Medknow Publications |
Subjects | |
Online Access | Get full text |
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Summary: | An attempt was made to study the antioxidant property of vitamin E in endosulfan and chlorpyrifos toxicity. Erythrocytes were collected from healthy rats and exposed to 1 ppm endosulfan and chlorpyrifos pesticides individually and also along with vitamin E treatment. Results showed that endosulfan was more toxic in comparison of chlorpyrifos. Activities of superoxide dismutase and catalase were significantly decreased, while lipid peroxidation and glutathione-S-transfarase were increased in comparison to the control values. The results of the present study suggest that vitamin E acts as an effective antioxidant for endosulfan and chlorpyrifos pesticide toxicity, in reducing oxidative stress burden. |
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ISSN: | 0971-6580 0976-5131 |
DOI: | 10.4103/0971-6580.75871 |