The use of GAFchromic film to determine the absolute activity of beta emitters

• Published in: Physics in medicine & biology Vol. 44; no. 4; pp. 833 - 842
• Main Authors: Fox, R A, Barker, P, Smart, G
• Format: Journal Article
• Language: English
• Published: Bristol IOP Publishing 01.04.1999; Institute of Physics
• Subjects: Applied radiobiology (equipment, dosimetry...); Beta Particles; Biological and medical sciences; Biological effects of radiation; Fundamental and applied biological sciences. Psychology; Nuclear Medicine - methods; Radiotherapy Planning, Computer-Assisted - instrumentation; Radiotherapy Planning, Computer-Assisted - methods; Tissues, organs and organisms biophysics; X-Ray Film; Treatment; Radiologic film; Correction factor; Dosimetry; Beta emitter; Calibration; Scintillation counter; Radiopharmaceuticals; Radiotherapy; Comparative study
• ISSN: 0031-9155; 1361-6560
• DOI: 10.1088/0031-9155/44/4/002

A method of using GAFchromic film to determine the absolute activity of beta emitters by immersing the film in a bath of activity is described. This includes calculations of the effect of part of the radioactive solution being displaced by the film that is performing the measurement. Calculations have been performed for 90Y, 32P and 188Re. It is shown that for the film used in this study, this effect will cause a correction of the order of 15-20% for the three radionuclides studied. The results of the GAFchromic film measurement are compared with results obtained from liquid scintillation counting and from a commercial dose calibrator. It is shown that for 32P all methods were in reasonable agreement, but for 188Re, although the GAFchromic film and the liquid scintillation counting methods give similar results, the dose calibrator measurement differed by more than 20%. The GAFchromic film was also used to perform a direct measurement of the radiation dose at a distance of 0.5 mm from the surface of a cylindrical source of 188Re activity. This gave good agreement with the value of the dose predicted from theoretical calculations.