Surface disinfection challenges for Candida auris: an in-vitro study

The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hos...

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Published inThe Journal of hospital infection Vol. 98; no. 4; pp. 433 - 436
Main Authors Kean, R., Sherry, L., Townsend, E., McKloud, E., Short, B., Akinbobola, A., Mackay, W.G., Williams, C., Jones, B.L., Ramage, G.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.04.2018
Subjects
Candida - drug effects
Candida - isolation & purification
Candida - physiology
Candida auris
Disinfectants - pharmacology
Disinfection
Environmental Microbiology
Microbial Viability - drug effects
Peracetic Acid - pharmacology
Sodium Hypochlorite - pharmacology
Surface
Candida auris
Disinfection
Surface
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Summary:The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.
Bibliography:ObjectType-Article-1
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ISSN:0195-6701
1532-2939
DOI:10.1016/j.jhin.2017.11.015