Poly(hexamethylene biguanide) salicylate as a novel ionic liquid with antibacterial properties in the production of poly(vinyl alcohol) films

• Published in: Materials research express Vol. 9; no. 9; pp. 95303 - 95313
• Main Authors: Słubik, Anna, Masłowska-Lipowicz, Iwona, Wieczorek, Dorota, Wyrębska, Łucja
• Format: Journal Article
• Language: English
• Published: Bristol IOP Publishing 01.09.2022
• Subjects: antibacterial properties; ionic liquid; Ionic liquids; Ions; Mechanical properties; Microorganisms; NMR; Nuclear magnetic resonance; PHMB-SA; poly(vinyl alcohol); Polyhexanide; Polyvinyl alcohol; Production methods; Tensile strength
• ISSN: 2053-1591; 2053-1591
• DOI: 10.1088/2053-1591/ac92cb

Abstract The presented work describes the effect of poly(hexamethylene biguanide) salicylate (PHMB-SA) ionic liquid on the properties of poly(vinyl alcohol) film. The ionic liquid synthetized is used as an antimicrobial agent. The ionic liquid consist of the poly(hexamethylene biguanide) cation and the salicylic anion, which exhibit synergistic antibacterial and bacteriostatic properties. The structure of obtained new ionic liquid was confirmed by infrared spectroscopy and nuclear magnetic resonance. Additionally, the article describes a simple method of producing an antibacterial PVA-based film with the addition of collagen and an ionic liquid. The study investigated the effect of the amount of the PHMB-SA on the mechanical properties, microorganism in liquid medium and the antibacterial properties of the PVA film. The obtained results indicate that the mechanical and antibacterial properties of the PVA/Col films depended on the amount of the ionic liquid. The higher value of the tensile strength (27.11 MPa) and the higher degree of microbial growth inhibition (7 mm) was obtained for the sample containing 0.75 g PHMB-SA.