Bacterial Persistence: Finding the “Sweet Spot”

Studies described by Eisele et al. (2013) and Xavier et al. (2013) in this issue of Cell Host & Microbe show that the bacterial pathogens Salmonella and Brucella exploit the increased levels of glucose present in alternatively activated macrophages to sustain chronic infections in experimentally...

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Bibliographic Details
Published inCell host & microbe Vol. 14; no. 2; pp. 119 - 120
Main Authors Roop, R. Martin, Caswell, Clayton C.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 14.08.2013
Subjects
Animals
Brucella abortus - physiology
Glucose - metabolism
Host-Pathogen Interactions
Macrophage Activation
Macrophages - microbiology
Microbial Viability
PPAR delta - metabolism
PPAR gamma - metabolism
Salmonella typhimurium - physiology
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Summary:Studies described by Eisele et al. (2013) and Xavier et al. (2013) in this issue of Cell Host & Microbe show that the bacterial pathogens Salmonella and Brucella exploit the increased levels of glucose present in alternatively activated macrophages to sustain chronic infections in experimentally infected mice.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Commentary-1
ISSN:1931-3128
1934-6069
DOI:10.1016/j.chom.2013.07.016