Risk factors for imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units in south China

• Published in: The Journal of hospital infection Vol. 98; no. 3; pp. 305 - 308
• Main Authors: Rao, Y.B., Ren, Z.X., Zhong, J.J., Zhong, X.M., Cao, B., Chen, D.M., Pan, X.N., Jia, Y.P., Gao, P.M., Yang, B.Y., Zhong, Q., Yang, J.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2018
• Subjects: Hospital-acquired infection; Imipenem; Neonate; Pseudomonas aeruginosa; Pseudomonas aeruginosa; Hospital-acquired infection; Neonate; Imipenem; Hospital-Acquired Infection
• ISSN: 0195-6701; 1532-2939
• DOI: 10.1016/j.jhin.2017.12.016

This multi-centre retrospective study was designed to investigate the risk factors for infection with imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units (NICUs) in south China. All patients with confirmed P. aeruginosa infection from eight NICUs in south China were divided into two groups: imipenem-susceptible P. aeruginosa and imipenem-resistant P. aeruginosa. Data were analysed using Chi-squared test and logistic regression. In total, 188 medical records were reviewed. On multi-variate logistic analysis, the only independent risk factor was imipenem treatment within two weeks of isolation of P. aeruginosa (odds ratio 6.409, 95% confidence interval 1.926–21.333).