Aster: A New Star in Cholesterol Trafficking

Life evolved in an aqueous environment, necessitating the evolution of carrier proteins to shuttle lipophilic molecules within and between cells. Sandhu et. al. (2018) report the discovery of a long-sought-after cholesterol carrier protein, named Aster, which transports cholesterol from the plasma m...

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Bibliographic Details
Published inCell Vol. 175; no. 2; pp. 307 - 309
Main Authors Kutyavin, Vassily I., Chawla, Ajay
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 04.10.2018
Subjects
Animals
Biological Transport
Cell Membrane
Cholesterol
Endoplasmic Reticulum
Proteins
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Summary:Life evolved in an aqueous environment, necessitating the evolution of carrier proteins to shuttle lipophilic molecules within and between cells. Sandhu et. al. (2018) report the discovery of a long-sought-after cholesterol carrier protein, named Aster, which transports cholesterol from the plasma membrane to the endoplasmic reticulum. Life evolved in an aqueous environment, necessitating the evolution of carrier proteins to shuttle lipophilic molecules within and between cells. Sandhu et. al. (2018) report the discovery of a long-sought-after cholesterol carrier protein, named Aster, which transports cholesterol from the plasma membrane to the endoplasmic reticulum.
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ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2018.09.025