Synthesis of a photoactivatable probe of the anandamide re-uptake

To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed...

Full description

Saved in:
Bibliographic Details
Published inNatural product research Vol. 19; no. 4; pp. 419 - 423
Main Authors Balas, Laurence, Hellal, Malik, Rossi, Jean-Claude, Durand, Thierry
Format Journal Article
LanguageEnglish
Published England Taylor & Francis Group 01.06.2005
Subjects
Anandamide re-uptake
Arachidonic Acids - chemistry
Arachidonic Acids - metabolism
Benzyl Compounds - chemistry
Endocannabinoid system
Endocannabinoids
Iodo-arylazido probe
Laboratory Chemicals - chemical synthesis
Laboratory Chemicals - chemistry
Molecular Structure
Photochemistry
Polyunsaturated Alkamides
Online AccessGet full text

Cover

More Information
Summary:To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anandamide transport process.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1478-6419
1478-6427
DOI:10.1080/14786410500057015