The advancements and prospective developments in anti-tumor targeted therapy

• Published in: Neoplasia (New York, N.Y.) Vol. 56; p. 101024
• Main Authors: Leng, Guorui, Duan, Baorong, Liu, Junjie, Li, Song, Zhao, Wenwen, Wang, Shanshan, Hou, Guige, Qu, Jiale
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2024; Neoplasia Press; Elsevier
• Subjects: Anti-tumor materials; Challenge and prospect; Immunotherapy; Review; Targeted therapy; Tumor microenvironment; Anti-tumor materials; Tumor microenvironment; Targeted therapy; Immunotherapy; Challenge and prospect
• ISSN: 1476-5586; 1522-8002; 1476-5586
• DOI: 10.1016/j.neo.2024.101024

Cancer poses a major threat to human health worldwide. The development of anti-tumor materials provides new modalities for cancer diagnosis and treatment. In this review, we comprehensively summarize the research progress and clinical applications of anti-tumor materials. First, we introduce the etiology and pathogenesis of cancer, and the significance and challenges of anti-tumor materials research. Then, we classify anti-tumor materials and discuss their mechanisms of action. After that, we elaborate the research advances and clinical applications of anti-tumor materials, including those targeting tumor cells and therapeutic instruments. Finally, we discuss the future perspectives and challenges in the field of anti-tumor materials. This review aims to provide an overview of the current status of anti-tumor materials research and application, and to offer insights into future directions in this rapidly evolving field, which holds promise for more precise, efficient and customized treatment of cancer. [Display omitted]