Solvent-free synthesis of pillar[6]arenes
An efficient solvent-free procedure for the synthesis of pillar[6]-arenes has been developed. The procedure involves the solid-state condensation of finely milled 1,4-dialkoxybenzene and paraformaldehyde by grinding in the presence of a catalytic amount of H2SO4. The use of organic solvents for the...
Saved in:
Published in | Green chemistry : an international journal and green chemistry resource : GC Vol. 18; no. 2; pp. 423 - 426 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
CAMBRIDGE
Royal Soc Chemistry
01.01.2016
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | An efficient solvent-free procedure for the synthesis of pillar[6]-arenes has been developed. The procedure involves the solid-state condensation of finely milled 1,4-dialkoxybenzene and paraformaldehyde by grinding in the presence of a catalytic amount of H2SO4. The use of organic solvents for the extraction of products has also been avoided. Operational simplicity, compatibility with various 1,4-dialkoxybenzenes, non-chromatographic purification technique, high yields and mild reaction conditions are the notable advantages of this procedure. A large scale reaction demonstrated the practical applicability of this methodology. |
---|---|
Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1463-9262 1463-9270 |
DOI: | 10.1039/c5gc01505g |