RELATIONSHIP OF GAIT AND COGNITION IN THE ELDERLY

Gait and cognitive impairments in older adults mostly reflect the co-occurrence of two geriatric syndromes linked by common underlying brain substrates and pathologies. Gait control is predominately mediated by frontal subcortical circuits, which overlap with circuits controlling executive control a...

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Bibliographic Details
Published inCurrent geriatrics reports Vol. 2; no. 3; pp. 167 - 173
Main Authors Parihar, Raminder, Mahoney, Jeannette R, Verghese, Joe
Format Journal Article
LanguageEnglish
Published United States Springer Nature B.V 01.09.2013
Subjects
Age
Aging
Attention
Clinical medicine
Cognition & reasoning
Dementia
Executive function
Gait
Geriatrics
Memory
Mobility
Older people
Pathology
Velocity
Walking
United States > US
remediation
dementia risk
Gait
cognition
inflammation
neurodegeneration
gait phenotypes
dual-task
quantitative gait measurements
vascular
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Summary:Gait and cognitive impairments in older adults mostly reflect the co-occurrence of two geriatric syndromes linked by common underlying brain substrates and pathologies. Gait control is predominately mediated by frontal subcortical circuits, which overlap with circuits controlling executive control and attention functions. These circuits are vulnerable to multiple age-related pathologies such as ischemia, inflammation, and neurodegeneration, which could ultimately cause cognitive, gait, or combined cognitive and gait impairments. The following review aims to describe various gait and cognitive classifications, gait based phenotypes, common underlying pathological processes, and provide a link between motor and cognitive impairments in an effort to predict the risk of dementia, as well as remediate impairments by applying appropriate interventions.
ISSN:2162-4941
2196-7865
2162-4941
2196-7865
DOI:10.1007/s13670-013-0052-7