Future AAVenues for In Utero Gene Therapy
Fetal gene therapy using safe and effective viral vectors no longer remains a distant prospect. Recently in Nature Medicine, Massaro et al. (2018) demonstrated that prenatal intracranial injection of a viral vector results in improved neurologic function, raising the intriguing possibility that in u...
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Published in | Cell stem cell Vol. 23; no. 3; pp. 320 - 321 |
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Elsevier Inc
06.09.2018
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Abstract | Fetal gene therapy using safe and effective viral vectors no longer remains a distant prospect. Recently in Nature Medicine, Massaro et al. (2018) demonstrated that prenatal intracranial injection of a viral vector results in improved neurologic function, raising the intriguing possibility that in utero gene therapy may be approaching clinical applications.
Fetal gene therapy using safe and effective viral vectors no longer remains a distant prospect. Recently in Nature Medicine, Massaro et al. (2018) demonstrated that prenatal intracranial injection of a viral vector results in improved neurologic function, raising the intriguing possibility that in utero gene therapy may be approaching clinical applications. |
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AbstractList | Fetal gene therapy using safe and effective viral vectors no longer remains a distant prospect. Recently in Nature Medicine, Massaro et al. (2018) demonstrated that prenatal intracranial injection of a viral vector results in improved neurologic function, raising the intriguing possibility that in utero gene therapy may be approaching clinical applications. Fetal gene therapy using safe and effective viral vectors no longer remains a distant prospect. Recently in Nature Medicine, Massaro et al. (2018) demonstrated that prenatal intracranial injection of a viral vector results in improved neurologic function, raising the intriguing possibility that in utero gene therapy may be approaching clinical applications. Fetal gene therapy using safe and effective viral vectors no longer remains a distant prospect. Recently in Nature Medicine, Massaro et al. (2018) demonstrated that prenatal intracranial injection of a viral vector results in improved neurologic function, raising the intriguing possibility that in utero gene therapy may be approaching clinical applications. |
Author | MacKenzie, Tippi C. |
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Cites_doi | 10.1182/blood-2004-02-0627 10.1038/sj.mt.6300219 10.1038/mtm.2016.20 10.1056/NEJMoa1708538 10.1056/NEJMoa1708483 10.1016/S1474-4422(17)30169-2 10.1089/10430340050015257 10.1038/s41591-018-0106-7 10.1056/NEJMoa1706198 10.1056/NEJMoa1714322 |
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SubjectTerms | Female Fetus Genetic Therapy Genetic Vectors Humans Infant Neurodegenerative Diseases Pregnancy |
Title | Future AAVenues for In Utero Gene Therapy |
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