Targeting immune cells within lymph nodes

Increased delivery to immune cells in the cortex and paracortex of the lymph node can be achieved by conjugating cargo to nanoparticles via linkers that release at programmable rates.

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Bibliographic Details
Published inNature nanotechnology Vol. 15; no. 6; pp. 423 - 425
Main Authors Porter, Christopher J. H., Trevaskis, Natalie L.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.06.2020
Nature Publishing Group
Subjects
639/925
639/925/352
Chemistry and Materials Science
Drug Delivery Systems
Immune system
Lymph Nodes
Materials Science
Nanoparticles
Nanotechnology
Nanotechnology and Microengineering
News & Views
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Summary:Increased delivery to immune cells in the cortex and paracortex of the lymph node can be achieved by conjugating cargo to nanoparticles via linkers that release at programmable rates.
Bibliography:ObjectType-Article-2
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ISSN:1748-3387
1748-3395
DOI:10.1038/s41565-020-0663-z