Simultaneous photo-induced cross-linking and silver nanoparticle formation in a PVP electrospun wound dressing

•UV irradiation of PVP with Ag induces crosslinking and nanoparticles formation.•Each process correlates with an absorption peak that evolves with irradiation time.•Irradiated fibers are stable in water and released Ag nanoparticles to the medium.•These fibers have antimicrobial activity adequate to...

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Bibliographic Details
Published inMaterials letters Vol. 207; pp. 145 - 148
Main Authors Rosa, Rita Morais, Silva, Jorge Carvalho, Sanches, Ilda Santos, Henriques, Célia
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 15.11.2017
Elsevier BV
Subjects
Ag nanoparticles
Antimicrobial agents
Antimicrobial effect
Bacteria
Crosslinking
Electrospinning
Fungi
Materials science
Mats
Nanofibers
Nanoparticles
PVP photo-crosslinking
Silver
Ultraviolet radiation
UV radiation
Wound dressing
Wound healing
UV radiation
Wound dressing
Ag nanoparticles
Antimicrobial effect
PVP photo-crosslinking
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Summary:•UV irradiation of PVP with Ag induces crosslinking and nanoparticles formation.•Each process correlates with an absorption peak that evolves with irradiation time.•Irradiated fibers are stable in water and released Ag nanoparticles to the medium.•These fibers have antimicrobial activity adequate to a wound dressing. Poly(N-vinylpyrrolidone) (PVP) nanofiber mats were electrospun from a solution containing silver nitrate and 254nm UV light was used to, simultaneously, photo-crosslink the polymer and promote silver nanoparticles (AgNP) formation. PVP cross-linking gives rise to a peak at 290nm in the UV–Vis spectrum while the surface plasmon resonance of AgNP appeared at 420nm. PVP-AgNP mats showed inhibitory effects on bacteria and fungi. This work shows that a PVP-AgNP wound dressing that ensures antimicrobial protection can be produced following a simple route.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2017.07.046