Breakthrough Moments: Genome Editing and Organoids

Six years ago, Schwank et al. (2013) adapted CRISPR-Cas9 and organoid technology to repair genetic diseases in patient-derived tissues. We shine a spotlight on how this work has inspired the development of tools to study and correct genetic diseases in experimental systems, with the ultimate goal of...

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Bibliographic Details
Published inCell stem cell Vol. 24; no. 6; pp. 841 - 842
Main Authors Roper, Jatin, Yilmaz, Ömer H.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 06.06.2019
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Summary:Six years ago, Schwank et al. (2013) adapted CRISPR-Cas9 and organoid technology to repair genetic diseases in patient-derived tissues. We shine a spotlight on how this work has inspired the development of tools to study and correct genetic diseases in experimental systems, with the ultimate goal of treating human disease. Six years ago, Schwank et al. (2013) adapted CRISPR-Cas9 and organoid technology to repair genetic diseases in patient-derived tissues. We shine a spotlight on how this work has inspired the development of tools to study and correct genetic diseases in experimental systems, with the ultimate goal of treating human disease.
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ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2019.05.008