Codeine Precipitating Serotonin Syndrome in a Patient in Therapy with Antidepressant and Triptan

The serotonin syndrome is a serioius medical condition due due to an intensive stimulation of setonin receptors. It is a rare, but severe, consequence of interaction between serotomimetic agents. This is a report of a 70-year-old woman steadily in therapy with venlafaxine and rizatriptan for migrain...

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Published inClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology Vol. 15; no. 3; pp. 292 - 295
Main Authors Milano, Giulia, Natta, Werner Maria, Bello, Alfredo, Martelli, Antonietta, Mattioli, Francesca
Format Journal Article
LanguageEnglish
Published Korea (South) Korean College of Neuropsychopharmacology 01.08.2017
대한정신약물학회
Subjects
Case Report
정신과학
Prescription drug misuse
Drug-drug interactions
Migraine disorders
Serotonin syndrome
Major depressive disorder
Codeine
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Abstract The serotonin syndrome is a serioius medical condition due due to an intensive stimulation of setonin receptors. It is a rare, but severe, consequence of interaction between serotomimetic agents. This is a report of a 70-year-old woman steadily in therapy with venlafaxine and rizatriptan for migraine and major depressive syndrome. She was admitted to neurology unit for decreased light reflex with miotic pupils, global hyperreflexia, tremor, anxiety, ataxia and incoordination. The patient was diagnosed as a probable case of serotonin syndrome due to a pharmacological interaction between venlafaxine and rizatriptan trigged by opioid intake. In this paper, the development of syntomatology, the clinical examination and the possible pharmacokinetics explanation were carefully discussed and analysed.
AbstractList The serotonin syndrome is a serioius medical condition due due to an intensive stimulation of setonin receptors. It is a rare, but severe, consequence of interaction between serotomimetic agents. This is a report of a 70-year-old woman steadily in therapy with venlafaxine and rizatriptan for migraine and major depressive syndrome. She was admitted to neurology unit for decreased light reflex with miotic pupils, global hyperreflexia, tremor, anxiety, ataxia and incoordination. The patient was diagnosed as a probable case of serotonin syndrome due to a pharmacological interaction between venlafaxine and rizatriptan trigged by opioid intake. In this paper, the development of syntomatology, the clinical examination and the possible pharmacokinetics explanation were carefully discussed and analysed.
The serotonin syndrome is a serioius medical condition due due to an intensive stimulation of setonin receptors. It is a rare, but severe, consequence of interaction between serotomimetic agents. This is a report of a 70-year-old woman steadily in therapy with venlafaxine and rizatriptan for migraine and major depressive syndrome. She was admitted to neurology unit for decreased light reflex with miotic pupils, global hyperreflexia, tremor, anxiety, ataxia and incoordination. The patient was diagnosed as a probable case of serotonin syndrome due to a pharmacological interaction between venlafaxine and rizatriptan trigged by opioid intake. In this paper, the development of syntomatology, the clinical examination and the possible pharmacokinetics explanation were carefully discussed and analysed. KCI Citation Count: 1
Author Martelli, Antonietta
Bello, Alfredo
Natta, Werner Maria
Mattioli, Francesca
Milano, Giulia
AuthorAffiliation 1 Department of Internal Medicine, Clinical Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy
2 Neurology Unit, Istituto Clinico ‘Salus’, Alessandria, Italy
AuthorAffiliation_xml – name: 1 Department of Internal Medicine, Clinical Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy
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  surname: Milano
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  givenname: Werner Maria
  surname: Natta
  fullname: Natta, Werner Maria
  organization: Neurology Unit, Istituto Clinico 'Salus', Alessandria, Italy
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  givenname: Alfredo
  surname: Bello
  fullname: Bello, Alfredo
  organization: Neurology Unit, Istituto Clinico 'Salus', Alessandria, Italy
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  givenname: Antonietta
  surname: Martelli
  fullname: Martelli, Antonietta
  organization: Department of Internal Medicine, Clinical Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy
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  givenname: Francesca
  surname: Mattioli
  fullname: Mattioli, Francesca
  organization: Department of Internal Medicine, Clinical Pharmacology and Toxicology Unit, University of Genoa, Genoa, Italy
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Cites_doi 10.1007/s00228-014-1676-z
10.1016/j.genhosppsych.2007.09.007
10.1136/bmj.330.7488.396
10.1016/j.puhe.2015.10.006
10.1007/s00415-014-7251-9
10.1176/ajp.148.6.705
10.1016/j.sapharm.2016.01.004
10.9758/cpn.2016.14.4.388
10.1093/bja/aei210
10.1016/j.bmcl.2013.06.084
10.1097/ALN.0b013e31823940c0
10.12659/AJCR.892264
10.1007/s00228-014-1748-0
10.1007/s12024-010-9188-3
10.1124/jpet.102.037861
10.4088/JCP.14m09394
10.5812/asjsm.28798
10.1016/S0278-5846(02)00338-X
10.1136/jnnp.57.12.1510
10.1097/00002826-200405000-00012
10.1093/qjmed/hcg109
10.4088/PCC.08l00690
10.1016/j.neuropharm.2007.07.009
10.1136/bmj.39559.675891.AD
10.1007/7854_2015_422
10.1097/WNF.0b013e31821b3aa0
10.1111/j.1365-2710.2007.00813.x
10.1345/aph.1E671
10.1097/JCP.0000000000000344
10.1007/s40263-012-0002-5
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Issue 3
Keywords Prescription drug misuse
Drug-drug interactions
Migraine disorders
Serotonin syndrome
Major depressive disorder
Codeine
Language English
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대한정신약물학회
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References 19956471 - Prim Care Companion J Clin Psychiatry. 2009;11(5):273
2157700 - J Clin Psychiatry. 1990 Apr;51 Suppl:14-20; discussion 21
12551730 - Prog Neuropsychopharmacol Biol Psychiatry. 2003 Feb;27(1):85-102
12422548 - Therapie. 2002 May-Jun;57(3):309-10
21586918 - Clin Neuropharmacol. 2011 May-Jun;34(3):127-8
2035713 - Am J Psychiatry. 1991 Jun;148(6):705-13
18433663 - Gen Hosp Psychiatry. 2008 May-Jun;30(3):284-7
25217187 - Eur J Clin Pharmacol. 2014 Nov;70(11):1313-24
22037635 - Anesthesiology. 2011 Dec;115(6):1291-8
21052868 - Forensic Sci Med Pathol. 2011 Jun;7(2):162-84
7798982 - J Neurol Neurosurg Psychiatry. 1994 Dec;57(12):1510-7
16368927 - Ann Pharmacother. 2006 Jan;40(1):155-7
12388635 - J Pharmacol Exp Ther. 2002 Nov;303(2):549-56
16051647 - Br J Anaesth. 2005 Oct;95(4):434-41
15718539 - BMJ. 2005 Feb 19;330(7488):396
7562497 - J Pharmacol Exp Ther. 1995 Sep;274(3):1263-70
25540831 - Am J Case Rep. 2014 Dec 19;15:562-4
15190240 - Clin Neuropharmacol. 2004 May-Jun;27(3):150-1
26612458 - Public Health. 2016 Jan;130:95-6
23461451 - Farm Hosp. 2012 Nov-Dec;36(6):548
24214521 - J Popul Ther Clin Pharmacol. 2013;20(3):e369-96
12771076 - CMAJ. 2003 May 27;168(11):1439-42
17765930 - Neuropharmacology. 2007 Oct;53(5):643-56
23880538 - Bioorg Med Chem Lett. 2013 Sep 1;23(17):4870-4
26082973 - J Clin Psychopharmacol. 2015 Aug;35(4):382-8
27776393 - Clin Psychopharmacol Neurosci. 2016 Nov 30;14 (4):388-390
26845272 - J Clin Psychiatry. 2016 Jan;77(1):e1-7
26853833 - Res Social Adm Pharm. 2017 Jan - Feb;13(1):187-192
18092054 - MedGenMed. 2007 Sep 05;9(3):48
24477492 - J Neurol. 2014 Apr;261(4):686-95
17381671 - J Clin Pharm Ther. 2007 Apr;32(2):199-202
24793010 - Eur J Clin Pharmacol. 2014 Jul;70(7):849-57
25842648 - AANA J. 2014 Oct;82(5):340-5
18583683 - BMJ. 2008 Jun 28;336(7659):1502-4
26715976 - Asian J Sports Med. 2015 Dec;6(4):e28798
12925718 - QJM. 2003 Sep;96(9):635-42
26768736 - Curr Top Behav Neurosci. 2017;34:59-75
23018546 - CNS Drugs. 2012 Nov;26(11):949-57
ref13
ref35
ref12
ref34
ref15
ref37
ref14
ref36
ref31
ref30
ref11
ref33
ref10
ref32
ref2
ref1
ref17
ref39
ref16
ref38
ref19
ref18
ref24
ref23
ref26
ref25
ref20
ref22
ref21
ref28
ref27
ref29
ref8
ref7
ref9
ref4
ref3
ref6
ref5
References_xml – ident: ref3
  doi: 10.1007/s00228-014-1676-z
– ident: ref21
  doi: 10.1016/j.genhosppsych.2007.09.007
– ident: ref2
  doi: 10.1136/bmj.330.7488.396
– ident: ref29
– ident: ref18
  doi: 10.1016/j.puhe.2015.10.006
– ident: ref6
  doi: 10.1007/s00415-014-7251-9
– ident: ref27
– ident: ref23
  doi: 10.1176/ajp.148.6.705
– ident: ref1
  doi: 10.1016/j.sapharm.2016.01.004
– ident: ref9
  doi: 10.9758/cpn.2016.14.4.388
– ident: ref36
  doi: 10.1093/bja/aei210
– ident: ref19
  doi: 10.1016/j.bmcl.2013.06.084
– ident: ref35
  doi: 10.1097/ALN.0b013e31823940c0
– ident: ref28
  doi: 10.12659/AJCR.892264
– ident: ref14
  doi: 10.1007/s00228-014-1748-0
– ident: ref15
– ident: ref39
  doi: 10.1007/s12024-010-9188-3
– ident: ref30
– ident: ref38
  doi: 10.1124/jpet.102.037861
– ident: ref4
– ident: ref5
  doi: 10.4088/JCP.14m09394
– ident: ref17
  doi: 10.5812/asjsm.28798
– ident: ref7
  doi: 10.1016/S0278-5846(02)00338-X
– ident: ref20
  doi: 10.1136/jnnp.57.12.1510
– ident: ref32
  doi: 10.1097/00002826-200405000-00012
– ident: ref24
  doi: 10.1093/qjmed/hcg109
– ident: ref31
  doi: 10.4088/PCC.08l00690
– ident: ref22
  doi: 10.1016/j.neuropharm.2007.07.009
– ident: ref13
  doi: 10.1136/bmj.39559.675891.AD
– ident: ref16
  doi: 10.1007/7854_2015_422
– ident: ref10
  doi: 10.1097/WNF.0b013e31821b3aa0
– ident: ref34
  doi: 10.1111/j.1365-2710.2007.00813.x
– ident: ref37
  doi: 10.1345/aph.1E671
– ident: ref11
  doi: 10.1097/JCP.0000000000000344
– ident: ref26
– ident: ref8
– ident: ref25
  doi: 10.1007/s40263-012-0002-5
– ident: ref12
– ident: ref33
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Title Codeine Precipitating Serotonin Syndrome in a Patient in Therapy with Antidepressant and Triptan
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