Distributions of VIP, substance P, neurokinin A and neurotensin in rat heart: an immunocytochemical study

Vasoactive intestinal peptide (VIP) is a peptide amide containing 28 amino acids which was first isolated from the intestine and is distributed over the entire body but primarily in the nervous system. It is released in response to the electrical stimulation of nerve fibres, stimulation of the vagus...

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Bibliographic Details
Published inNeuropeptides (Edinburgh) Vol. 33; no. 1; pp. 19 - 25
Main Authors Onuoha, G.N., Alpar, E.K., Chukwulobelu, R., Nicholls, D.P.
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 01.02.1999
Elsevier
Subjects
Animals
Autonomic Nervous System - chemistry
Biological and medical sciences
Coronary Circulation - physiology
Fundamental and applied biological sciences. Psychology
Heart
Heart - innervation
Heart Atria - innervation
Heart Ventricles - innervation
Immunohistochemistry
Muscle, Smooth, Vascular - physiology
Nerve Fibers - chemistry
Neurokinin A - analysis
Neuropeptides - analysis
Neurotensin - analysis
Radioimmunoassay
Rats
Substance P - analysis
Vasoactive Intestinal Peptide - analysis
Vasoconstriction - physiology
Vertebrates: cardiovascular system
Heart
Rat
Immunocytochemistry
Substance P
Rodentia
Neurotensin
Neuropeptide
Vertebrata
Mammalia
Neurokinin A
Radioimmunoassay
Vasoactive intestinal peptide
Circulatory system
Localization
Tachykinin
Comparative study
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Summary:Vasoactive intestinal peptide (VIP) is a peptide amide containing 28 amino acids which was first isolated from the intestine and is distributed over the entire body but primarily in the nervous system. It is released in response to the electrical stimulation of nerve fibres, stimulation of the vagus, prostaglandin E1, oxytocin, operation stress, corticosterone. In the cardiovascular system, VIP has a vasodilation, hypotension, positive chronotropic and inotropic effects.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0143-4179
1532-2785
DOI:10.1054/npep.1999.0026