Salmonella Manipulates Autophagy to “Serve and Protect”

Many intracellular pathogens, including Salmonella typhimurium, trigger autophagy in host cells, which is widely thought to restrict intracellular growth and survival. In this issue of Cell Host & Microbe, Kreibich et al. (2015) demonstrate a role for the autophagic machinery in the repair of da...

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Bibliographic Details
Published inCell host & microbe Vol. 18; no. 5; pp. 517 - 519
Main Authors Owen, Katherine A., Casanova, James E.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 11.11.2015
Subjects
Autophagy
Cytoplasm
Humans
Salmonella Infections
Salmonella typhimurium
Vacuoles
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Summary:Many intracellular pathogens, including Salmonella typhimurium, trigger autophagy in host cells, which is widely thought to restrict intracellular growth and survival. In this issue of Cell Host & Microbe, Kreibich et al. (2015) demonstrate a role for the autophagic machinery in the repair of damaged Salmonella-containing vacuoles (SCVs). Many intracellular pathogens, including Salmonella typhimurium, trigger autophagy in host cells, which is widely thought to restrict intracellular growth and survival. In this issue of Cell Host & Microbe, Kreibich et al. demonstrate a role for the autophagic machinery in the repair of damaged Salmonella-containing vacuoles (SCVs).
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ISSN:1931-3128
1934-6069
DOI:10.1016/j.chom.2015.10.020