Keeping the customers stratified: moving toward genetics-based treatment options in childhood NS

In this issue, Bierzynska et al. report the results of analyzing a cohort of children with steroid-resistant nephrotic syndrome (SRNS) of childhood, correlating genetic studies with clinical outcomes. This approach has the potential to advance both our research into the causes and treatments of chil...

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Published inKidney international Vol. 91; no. 4; pp. 781 - 783
Main Authors Puckelwartz, Megan, Schnaper, H. William
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.04.2017
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Summary:In this issue, Bierzynska et al. report the results of analyzing a cohort of children with steroid-resistant nephrotic syndrome (SRNS) of childhood, correlating genetic studies with clinical outcomes. This approach has the potential to advance both our research into the causes and treatments of childhood SRNS and our ability to stratify patients into groups that are likely to be responsive to specific treatments. Here, we discuss some of the strengths and limitations of this report.
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ISSN:0085-2538
1523-1755
DOI:10.1016/j.kint.2016.12.032