Dioctylamine-Sulfonamide-Modified Carbon Nanoparticles as High Surface Area Substrates for Coenzyme Q10Lipid Electrochemistry

• Published in: Electroanalysis (New York, N.Y.) Vol. 24; no. 5; pp. 1003 - 1010
• Main Authors: Lawrence, Katherine, Watkins, John D., James, Tony D., Taylor, James E., Bull, Steven D., Nelson, Geoffrey W., Foord, John S., Long, Yi-Tao, Marken, Frank
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.05.2012; WILEY‐VCH Verlag
• Subjects: Capacitance; Carbon; Carbon nanoparticles; Cell wall; Coenzymes; Deposits; DMPC; Double layer; Electrolytes; Hydrophobicity; Lipid; Membrane; Nanoparticles; Q10; Reproducibility; Surface area; Thin film; Voltammetry
• ISSN: 1040-0397; 1521-4109
• DOI: 10.1002/elan.201200121

Dioctylaminesulfonamide‐modified carbon nanoparticles are characterised and employed as high surface area substrate for (i) coenzyme Q10 and (ii) 1,2‐dimyristoyl‐sn‐glycero‐3‐phosphocholine (or DMPC) ‐ Q10 redox processes. The carbon nanoparticles provide a highly hydrophobic substrate with ca. 25 Fg−1 capacitance when bare. Q10 or DMPC‐Q10 immobilised onto the carbon nanoparticles lower the capacitance, but give rise to well‐defined pH‐dependent voltammetric responses. The DMPC‐Q10 deposit shows similar characteristics to those of Q10, but with better reproducibility and higher sensitivity. Both redox systems, Q10 and DMPC‐Q10, are sensitive to the Na+ concentration in the electrolyte and mechanistic implications are discussed.