Sensing capability of molecularly imprinted self-assembled monolayer fabricated using dithiol compound

• Published in: Journal of industrial and engineering chemistry (Seoul, Korea) Vol. 20; no. 1; pp. 91 - 95
• Main Authors: Shin, Min Jae, Shin, Young Jae, Shin, Jae Sup
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.01.2014; 한국공업화학회
• Subjects: Cholesterol; Cyclic voltammogram; Detection; Dithiol compound; Functional groups; Microbalances; Molecular imprinting; Quartz crystals; Self-assembled monolayer; Self-assembled monolayers; Sensor; Solvent extraction; Stability; Synthesis; 화학공학; Dithiol compound; Self-assembled monolayer; Molecular imprinting; Cholesterol; Cyclic voltammogram; Sensor
• ISSN: 1226-086X; 1876-794X
• DOI: 10.1016/j.jiec.2013.04.022

Synthesis of 3,5-di(6-mercaptohexyloxy)toluene (DMHT) was achieved starting from orcinol. A molecularly imprinted self-assembled monolayer (SAM) was fabricated by forming an SAM with both DMHT and the template molecule (cholesterol), followed by removal of the template molecules by solvent extraction. These imprinted SAMs were capable of discriminating the imprinted substrate. The stability of the imprinted SAMs was estimated precisely using a quartz crystal microbalance. In comparison to the results used monothiol compounds, the duration of the sensing capability of this imprinted SAM was improved greatly. The two thiol functional groups in DMHT clearly had a significant effect on the duration.