Is intact PTH a sensitive biochemical indicator of deranged calcium homeostasis in vitamin D deficiency?

Intact PTH was elevated in 38/40 Asians with reduced serum 25 hydroxyvitamin D [25(OH)D] including seven patients with normal serum calcium, phosphate and alkaline phosphatase. Changes in intact PTH were disproportionately greater than for other biochemical parameters, making it the most sensitive e...

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Bibliographic Details
Published inAnnals of clinical biochemistry Vol. 26 ( Pt 4); p. 324
Main Authors Ashby, J P, Newman, D J, Rinsler, M G
Format Journal Article
LanguageEnglish
Published England 01.07.1989
Subjects
Ascorbic Acid Deficiency - blood
Ascorbic Acid Deficiency - complications
Calcium - blood
Cohort Studies
Homeostasis
Humans
Hyperparathyroidism, Secondary - blood
Hyperparathyroidism, Secondary - epidemiology
Hyperparathyroidism, Secondary - etiology
Parathyroid Hormone - blood
Retrospective Studies
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Summary:Intact PTH was elevated in 38/40 Asians with reduced serum 25 hydroxyvitamin D [25(OH)D] including seven patients with normal serum calcium, phosphate and alkaline phosphatase. Changes in intact PTH were disproportionately greater than for other biochemical parameters, making it the most sensitive early indicator of deranged calcium homeostasis in vitamin D deficiency.
ISSN:0004-5632
DOI:10.1177/000456328902600404