Oral endotracheal intubation of rats for intratracheal instillation and aerosol drug delivery

As reported in the literature, oral endotracheal intubation of rats is considered to be very difficult. Specialised equipment and complicated techniques have been described to perform this procedure. In our experiment we adopted a simple method, which allowed—without any complicated equipment-the in...

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Bibliographic Details
Published inLaboratory animals (London) Vol. 35; no. 3; pp. 257 - 260
Main Authors Lizio, R, Westhof, A, Lehr, C M, Klenner, T
Format Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.07.2001
Subjects
Administration, Inhalation
Administration, Oral
Aerosols
Animals
Drug Delivery Systems - veterinary
Intubation, Intratracheal - methods
Intubation, Intratracheal - veterinary
Male
Rats
Rats, Sprague-Dawley
DRUG
INTRATRACHEAL
TUBE
AEROSOL
ADMINISTRATION
LARGE
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Summary:As reported in the literature, oral endotracheal intubation of rats is considered to be very difficult. Specialised equipment and complicated techniques have been described to perform this procedure. In our experiment we adopted a simple method, which allowed—without any complicated equipment-the insertion of a relatively wide tube into the trachea of rats, allowing drug administration.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0023-6772
1758-1117
DOI:10.1258/0023677011911723