The human mycobiome in health and disease

The mycobiome, referring primarily to the fungal biota in an environment, is an important component of the human microbiome. Despite its importance, it has remained understudied. New culture-independent approaches to determine microbial diversity, such as next-generation sequencing methods, are grea...

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Published inGenome medicine Vol. 5; no. 7; p. 63
Main Authors Cui, Lijia, Morris, Alison, Ghedin, Elodie
Format Journal Article
LanguageEnglish
Published England BioMed Central 30.07.2013
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Review
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Summary:The mycobiome, referring primarily to the fungal biota in an environment, is an important component of the human microbiome. Despite its importance, it has remained understudied. New culture-independent approaches to determine microbial diversity, such as next-generation sequencing methods, are greatly broadening our view of fungal importance. An integrative analysis of current studies shows that different body sites harbor specific fungal populations, and that diverse mycobiome patterns are associated with various diseases. By interfacing with other biomes, as well as with the host, the mycobiome probably contributes to the progression of fungus-associated diseases and plays an important role in health and disease.
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ISSN:1756-994X
1756-994X
DOI:10.1186/gm467