Fixed-dose Combination of Dapagliflozin and Linagliptin in Individuals with Type 2 Diabetes Mellitus Inadequately Controlled on Metformin: A Randomized Double-blind Multicenter Trial

• Published in: Journal of diabetology Vol. 16; no. 1; pp. 50 - 56
• Main Authors: Kumthekar, Prashant, Upadhyay, Mihir R., Tamma, Rajasekhara Reddy, Kranti, Vijay, Bhattacharya, Raja, Sharma, Prabhat Kumar, Barge, Vijaykumar Bhagwan, Revankar, Santosh, Ghatge, Shweta
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer - Medknow 2025
• Edition: 3
• Subjects: Original Article; type 2 diabetes mellitus; metformin; linagliptin; Dapagliflozin; fixed-dose combination; glycated hemoglobin

Abstract Context: Combining dipeptidyl peptidase 4 inhibitors and sodium-glucose cotransporter-2 inhibitors in therapy could be beneficial for those with metformin intolerance or not achieving adequate control. Aims: To evaluate the efficacy, safety, and tolerability of a fixed-dose combination (FDC...