Anti-HSV activity of Hypnea musciformis cultured with different phytohormones

Four extracts from the seaweed Hypnea musciformis (Wulfen in Jacq.) J.V. Lamour. (Rhodophyta), collected directly from its natural habitat or cultivated in the presence of phytohormones, were evaluated for their ability to inhibit the replication of acyclovir-resistant herpes simplex viruses types 1...

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Published inRevista brasileira de farmacognosia Vol. 22; no. 4; pp. 789 - 794
Main Authors Mendes, Gabriella da Silva, Bravin, Isolda Cecília, Yoneshigue-Valentin, Yocie, Yokoya, Nair S., Romanos, Maria Teresa Villela
Format Journal Article
LanguageEnglish
Portuguese
Published Sociedade Brasileira de Farmacognosia 01.08.2012
Subjects
PHARMACOLOGY & PHARMACY
HSV-1
antiviral activity
Hypnea musciformis
HSV-2
phytohormones
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Summary:Four extracts from the seaweed Hypnea musciformis (Wulfen in Jacq.) J.V. Lamour. (Rhodophyta), collected directly from its natural habitat or cultivated in the presence of phytohormones, were evaluated for their ability to inhibit the replication of acyclovir-resistant herpes simplex viruses types 1 (HSV-1) and 2 (HSV-2) strains. The main purpose was to determinate whether these growth conditions would affect the antiviral activity. Our results showed the possibility of improving the anti-HSV activity by using extracts from algae cultured in the presence of phytohormones.
ISSN:0102-695X
1981-528X
DOI:10.1590/S0102-695X2012005000054