Natural occurrence and synthesis of 2′-oxygenated flavones, flavonols, flavanones and chalcones

• Published in: Phytochemistry Vol. 28; no. 3; pp. 681 - 694
• Main Authors: Iinuma, Munekazu, Mizuno, Mizuo
• Format: Book Review Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 1989; Elsevier
• Subjects: 13C NMR; Analytical, structural and metabolic biochemistry; Aromatic and heterocyclic compounds; Biological and medical sciences; chemical character of 2′-oxygenated flavonoid; Fundamental and applied biological sciences. Psychology; Heterocyclic compounds, pigments; Occurrence of 2′-oxygenated flavonoid; Other biological molecules; chemical character of 2′-oxygenated flavonoid; 13C NMR; Occurrence of 2′-oxygenated flavonoid; Vegetals; Oxidation; NMR spectrometry; Flavonoid
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/0031-9422(89)80094-9

Two hundred and seventy-two flavonoids (flavones, flavonols, flavanones and chalcones) oxygenated at C-2′(C-2 in the case of chalcones), which have been obtained as natural products and prepared by partial derivation or by total synthesis are surveyed according to their oxygenation patterns. Plausible biosynthetic pathways are suggested for 2′-oxygenated flavonoids, their chemistry and 13C NMR spectra are summarized.