The effect on IVF outcome of small intramural fibroids not compressing the uterine cavity as determined by a prospective matched control study
BACKGROUND: Several studies have reported that the presence of intramural fibroids affects conception following IVF. We attempted to corroborate or refute the conclusions relating to IVF and leiomyomas of the aforementioned studies. METHODS: Women with small intramural leiomyomata (≤5 cm) discovered...
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Published in | Human reproduction (Oxford) Vol. 17; no. 5; pp. 1244 - 1248 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Oxford University Press
01.05.2002
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Subjects | |
Online Access | Get full text |
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Summary: | BACKGROUND: Several studies have reported that the presence of intramural fibroids affects conception following IVF. We attempted to corroborate or refute the conclusions relating to IVF and leiomyomas of the aforementioned studies. METHODS: Women with small intramural leiomyomata (≤5 cm) discovered on initial pelvic sonographic studies performed in preparation for IVF were prospectively matched by age, with the next patient of the same age undergoing IVF who did not demonstrate fibroids (controls). RESULTS: Though no significant differences were found in outcome when comparing these two groups, there was a distinct trend for lower live delivery rates and higher miscarriage rates. CONCLUSIONS: These data support the conclusions of the only other prospective matched control study evaluating similar factors, i.e. that small intramural fibroids can negatively affect IVF outcome. Nevertheless, we think that a multicentre study should be conducted first before evaluating whether myomectomy improves outcome or not. |
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Bibliography: | istex:64F166017D0B9D6F204B618F21BAEAE2CE4CA195 local:0171244 ark:/67375/HXZ-MV8KVCGG-Z PII:1460-2350 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 0268-1161 1460-2350 1460-2350 |
DOI: | 10.1093/humrep/17.5.1244 |