Imaging Tau Deposits In Vivo: Progress in Viewing More of The Proteopathy Picture

• Published in: Neuron (Cambridge, Mass.) Vol. 79; no. 6; pp. 1035 - 1037
• Main Authors: Mathis, Chester A., Klunk, William E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 18.09.2013; Elsevier Limited
• Subjects: Alzheimer Disease - pathology; Animals; Brain; Brain - pathology; Brain research; Clinical trials; Disease; Female; Human subjects; Humans; Ligands; Load; Male; Medical imaging; Retention; Rodents; Studies; tau Proteins - metabolism; Tauopathies - pathology

In this issue of Neuron, Maruyama et al. (2013) demonstrate the binding of a new class of selective tau ligands, termed PBBs, to tau deposits in transgenic mice and in human subjects with normal cognition, Alzheimer’s disease, or a corticobasal syndrome.