Imaging Tau Deposits In Vivo: Progress in Viewing More of The Proteopathy Picture

In this issue of Neuron, Maruyama et al. (2013) demonstrate the binding of a new class of selective tau ligands, termed PBBs, to tau deposits in transgenic mice and in human subjects with normal cognition, Alzheimer’s disease, or a corticobasal syndrome.

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Bibliographic Details
Published inNeuron (Cambridge, Mass.) Vol. 79; no. 6; pp. 1035 - 1037
Main Authors Mathis, Chester A., Klunk, William E.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 18.09.2013
Elsevier Limited
Subjects
Alzheimer Disease - pathology
Animals
Brain
Brain - pathology
Brain research
Clinical trials
Disease
Female
Human subjects
Humans
Ligands
Load
Male
Medical imaging
Retention
Rodents
Studies
tau Proteins - metabolism
Tauopathies - pathology
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Summary:In this issue of Neuron, Maruyama et al. (2013) demonstrate the binding of a new class of selective tau ligands, termed PBBs, to tau deposits in transgenic mice and in human subjects with normal cognition, Alzheimer’s disease, or a corticobasal syndrome.
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ISSN:0896-6273
1097-4199
1097-4199
DOI:10.1016/j.neuron.2013.09.001