Advances in Bovine Coronavirus Epidemiology

• Published in: Viruses Vol. 14; no. 5; p. 1109
• Main Authors: Zhu, Qinghe, Li, Bin, Sun, Dongbo
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.05.2022; MDPI
• Subjects: Age groups; Animal diseases; Animals; Beef cattle; bovine coronavirus; Cattle; Cattle Diseases - epidemiology; Coronavirus, Bovine - genetics; Coronaviruses; COVID-19 - veterinary; cross-species transmission; Dairy cattle; Diarrhea; Disease transmission; Epidemics; Epidemiology; Evolution & development; Evolution, Molecular; genetic evolution; Histology; Infections; Pathogenicity; Pathogens; Respiratory diseases; Review; Reviews; SARS-CoV-2 - genetics; Serology; Severe acute respiratory syndrome coronavirus 2; Viruses; Canada; Belgium; Asia; United States > US; Europe; China; Africa; Italy; Ghana; Australia; Oceania; cross-species transmission; epidemiology; genetic evolution; bovine coronavirus
• ISSN: 1999-4915; 1999-4915
• DOI: 10.3390/v14051109

Bovine coronavirus (BCoV) is a causative agent of enteric and respiratory disease in cattle. BCoV has also been reported to cause a variety of animal diseases and is closely related to human coronaviruses, which has attracted extensive attention from both cattle farmers and researchers. However, there are few comprehensive epidemiological reviews, and key information regarding the effect of S-gene differences on tissue tendency and potential cross-species transmission remain unclear. In this review, we summarize BCoV epidemiology, including the transmission, infection-associated factors, co-infection, pathogenicity, genetic evolution, and potential cross-species transmission. Furthermore, the potential two-receptor binding motif system for BCoV entry and the association between BCoV and SARS-CoV-2 are also discussed in this review. Our aim is to provide valuable information for the prevention and treatment of BCoV infection throughout the world.