Multiple Sclerosis in Patients with Intracranial Aneurysms: Coincidence or Correlation?

•Genetic associations of MS and intracranial aneurysms have been described•Occurrence of intracranial aneurysms in MS patients may be underestimated•Clinicians should be vigilant for atypical symptoms in MS patients

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Bibliographic Details
Published inClinical neurology and neurosurgery Vol. 195; p. 105864
Main Authors Walker, Melanie, Young, Christopher C., Levitt, Michael R., Saal-Zapata, Giancarlo
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.08.2020
Elsevier Limited
Subjects
Adult
aneurysm
Aneurysms
Aortic aneurysms
Arteriosclerosis
Autoimmune diseases
Biomarkers
Carotid arteries
Cathepsin B
CCL20 protein
Chemokines
Cytokines
Endothelial cells
Extracellular matrix
Family medical history
Female
Helper cells
Humans
Inflammation
Interleukins
Intracranial Aneurysm - complications
Lymphocytes
Lymphocytes T
Magnetic resonance imaging
Male
Matrix metalloproteinase
Medical imaging
Middle Aged
Multiple sclerosis
Multiple Sclerosis, Relapsing-Remitting - complications
Neurology
Pathogenesis
Proteolysis
Proteolytic enzymes
Tumor necrosis factor-α
vascular
Veins & arteries
Volcanoes
γ-Interferon
aneurysm
inflammation
vascular
multiple sclerosis
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More Information
Summary:•Genetic associations of MS and intracranial aneurysms have been described•Occurrence of intracranial aneurysms in MS patients may be underestimated•Clinicians should be vigilant for atypical symptoms in MS patients
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2020.105864