Metabolic Resistance in Bed Bugs

Blood-feeding insects have evolved resistance to various insecticides (organochlorines, pyrethroids, carbamates, etc.) through gene mutations and increased metabolism. Bed bugs (Cimex lectularius) are hematophagous ectoparasites that are poised to become one of the major pests in households througho...

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Bibliographic Details
Published inInsects Vol. 2; no. 1; pp. 36 - 48
Main Authors Mamidala, Praveen, Jones, Susan C, Mittapalli, Omprakash
Format Journal Article Book Review
LanguageEnglish
Published Switzerland MDPI AG 18.03.2011
MDPI
Subjects
Cimex lectularius
cytochrome P450
glutathione S-transferase
insecticides
metabolic resistance
Review
cytochrome P450
metabolic resistance
insecticides
Cimex lectularius
glutathione S-transferase
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Summary:Blood-feeding insects have evolved resistance to various insecticides (organochlorines, pyrethroids, carbamates, etc.) through gene mutations and increased metabolism. Bed bugs (Cimex lectularius) are hematophagous ectoparasites that are poised to become one of the major pests in households throughout the United States. Currently, C. lectularius has attained a high global impact status due to its sudden and rampant resurgence. Resistance to pesticides is one factor implicated in this phenomenon. Although much emphasis has been placed on target sensitivity, little to no knowledge is available on the role of key metabolic players (e.g., cytochrome P450s and glutathione S-transferases) towards pesticide resistance in C. lectularius. In this review, we discuss different modes of resistance (target sensitivity, penetration resistance, behavioral resistance, and metabolic resistance) with more emphasis on metabolic resistance.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:2075-4450
2075-4450
DOI:10.3390/insects2010036