Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment

Abstract Aim To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG). Patients and methods A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 Jan...

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Bibliographic Details
Published inInternational journal of mycobacteriology Vol. 4; no. 5; p. 151
Main Authors Smaoui, S, Mezghanni, M.A, Hammami, B, Zalila, N, Marouane, C, Kammoun, S, Ghorbel, A, Ben Jemaa, M, Messadi-Akrout, F
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.03.2015
Medknow Publications and Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Subjects
Care and treatment
Diagnosis
Epidemiology
Infectious Disease
Lymphadenitis
Medical Education
Microbiology
Treatment
Tuberculosis
Tuberculous lymphadenitis
Tunisia
Treatment
Tuberculous lymphadenitis
Microbiology
Epidemiology
Tunisia
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Summary:Abstract Aim To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG). Patients and methods A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 2009 and 16 June 2013. Results A total of 181 clinical files were examined. Mean age was 32 years old; the female/male ratio was 1.78 to 1. Raw milk consumption was noted in 1/3 of patients. Most cases involved the head and neck region (83.4%), nodes involvement, including axillary (12 cases), and mediastinal (9 cases). Clinical symptoms were present in only 55.2%. TST was conducted with 82.6% positive responses. Diagnostics confirmation was done with anatomical pathology in most of the patients; only 56 of them had any microbiology analysis done. Demonstration of acid-fast bacilli in microscopy from either fine-needle aspirates or biopsies was done in 17.5%, and cultures yielded positive results in 27%. Treatment duration was varied. Paradoxical reactions were noted in 12% and persistent lymphadenopathy after treatment completion was noted in 10% of cases. Conclusions TBG remains a disease of interest. Today, its diagnosis and management is still a problem despite its increasing worldwide incidence, and especially in this study area. Disease control should be strengthened in this country.
ISSN:2212-5531
2212-554X
DOI:10.1016/j.ijmyco.2014.10.022