Enterovirus D68-Associated Acute Flaccid Myelitis, United States, 2020

Acute flaccid myelitis (AFM) is a serious neurologic condition that causes limb weakness or paralysis in previously healthy children. Since clusters of cases were first reported in 2014, nationwide surveillance has demonstrated sharp increases in AFM cases in the United States every 2 years, most oc...

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Bibliographic Details
Published inEmerging infectious diseases Vol. 26; no. 10; pp. 6 - 12
Main Authors Kidd, Sarah, Lopez, Adriana S, Konopka-Anstadt, Jennifer L, Nix, W Allan, Routh, Janell A, Oberste, M Steven
Format Journal Article
LanguageEnglish
Published United States Centers for Disease Control and Prevention 01.10.2020
Subjects
acute flaccid myelitis
Antibodies
Cell culture
central nervous system viral diseases
Disease control
enterovirus infections
Epidemics
Epidemiology
Etiology
EV-D68
Guillain-Barre syndrome
Illnesses
Infections
Magnetic resonance imaging
Medical laboratories
Online Report
Paralysis
Pathogens
Pediatrics
Poliomyelitis
Respiratory diseases
United States
Viral infections
viruses
United States > US
Colorado
viruses
central nervous system viral diseases
EV-D68
United States
enterovirus infections
acute flaccid myelitis
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Summary:Acute flaccid myelitis (AFM) is a serious neurologic condition that causes limb weakness or paralysis in previously healthy children. Since clusters of cases were first reported in 2014, nationwide surveillance has demonstrated sharp increases in AFM cases in the United States every 2 years, most occurring during late summer and early fall. Given this current biennial pattern, another peak AFM season is expected during fall 2020 in the United States. Scientific understanding of the etiology and the factors driving the biennial increases in AFM has advanced rapidly in the past few years, although areas of uncertainty remain. The Centers for Disease Control and Prevention and AFM partners are focused on answering key questions about AFM epidemiology and mechanisms of disease. This article summarizes the current understanding of AFM etiology and outlines priorities for surveillance and research as we prepare for a likely surge in cases in 2020.
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ISSN:1080-6040
1080-6059
DOI:10.3201/eid2610.201630