Assessment of pre-extubating recurrent laryngeal nerve palsy using ultrasound in postoperative patients with esophageal cancer: a prospective observational study

• Published in: Journal of anesthesia Vol. 38; no. 3; pp. 347 - 353
• Main Authors: Kaneko, Tomomi, Kato, Takao, Shiko, Yuki, Kawasaki, Yohei, Koyama, Kaoru
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.06.2024
• Subjects: Aged; Airway Extubation - methods; Anesthesiology; Critical Care Medicine; Emergency Medicine; Esophageal Neoplasms - surgery; Female; Humans; Intensive; Male; Medicine; Medicine & Public Health; Middle Aged; Original; Original Article; Pain Medicine; Postoperative Complications - diagnosis; Postoperative Complications - diagnostic imaging; Prospective Studies; Recurrent Laryngeal Nerve - diagnostic imaging; Reproducibility of Results; Sensitivity and Specificity; Ultrasonography - methods; Vocal Cord Paralysis - diagnostic imaging; Vocal Cord Paralysis - etiology; Vocal cords; Ultrasound; Surgery; Esophageal cancer; Recurrent nerve palsy
• ISSN: 0913-8668; 1438-8359; 1438-8359
• DOI: 10.1007/s00540-024-03315-7

Purpose Ultrasound performed after extubation has been suggested to be useful for the diagnosis of recurrent laryngeal nerve (RLN) paralysis. However, the use of ultrasound for this purpose before extubation has not been examined. The aim of this study was to examine the versatility (interrater reliability) and usefulness of ultrasound for evaluating the movement of vocal cords before extubation. Methods The subjects were 30 patients who underwent radical surgery for esophageal cancer from August 2020 to December 2021. An experienced examiner performed an ultrasound examination before and after elective extubation on the day after surgery to evaluate RLN paralysis and record videos. Bronchoscopy was then performed to make a definite diagnosis. Three anesthetists blinded to the diagnosis also evaluated the cases using the videos, and the versatility of the examination was determined using a kappa test. Results The diagnostic accuracies of the examiner and three anesthetists were 76.7%, 50.0%, 53.3%, and 46.7%, respectively, and the kappa coefficients for the examiner with the anesthetists were 0.310, 0.502, and 0.169, respectively. The sensitivity, specificity, positive predictive value and negative predictive value for diagnosis of RLN paralysis by the examiner using ultrasound before extubation were 0.57, 0.95, 0.80, and 0.87, respectively. Conclusion These results indicate a lack of versatility of the ultrasound examination based on the low kappa coefficients. However, with an experienced examiner, ultrasound can serve as a non-invasive examination that can be performed before extubation with high accuracy and specificity for diagnosis of postoperative RLN paralysis.