Recent advances in polysaccharide-based self-healing hydrogels for biomedical applications

• Published in: Carbohydrate polymers Vol. 283; p. 119161
• Main Authors: Yang, Yongyan, Xu, Lifeng, Wang, Jingfei, Meng, Qingye, Zhong, Shuangling, Gao, Yan, Cui, Xuejun
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.05.2022
• Subjects: Alginates - chemistry; Animals; Bandages; biocompatibility; Biocompatible Materials - chemistry; Biocompatible Materials - pharmacology; biodegradability; Biodegradation, Environmental; Biomedical applications; biomimetics; Biomimetics - methods; Cell Culture Techniques - methods; Cellulose - chemistry; Drug Delivery Systems - methods; drugs; durability; Humans; Hydrogel; hydrogels; Hydrogels - chemistry; Hydrogels - pharmacology; Hydrogen Bonding; medicine; Mice; polymers; Polymers - chemistry; Polysaccharide; polysaccharides; Polysaccharides - chemistry; Polysaccharides - pharmacology; Self-healing; Tissue Engineering - methods; Water - chemistry; Wound Healing - drug effects; Self-healing; Biomedical applications; Hydrogel; Polysaccharide
• ISSN: 0144-8617; 1879-1344; 1879-1344
• DOI: 10.1016/j.carbpol.2022.119161

Hydrogels are a class of polymer materials with three-dimensional networks structure, which can absorb a large number of water and biological fluids. Natural polysaccharides are ideal materials for the preparation of biomimetic hydrogels because of their good biocompatibility and biodegradability. The self-healing hydrogel can achieve healing without external force and prolong the service life of the hydrogel. Therefore, self-healing hydrogels are of great interest in tissue engineering, wound dressings, drug delivery, and tissue engineering. This review aims to introduce the preparation methods, self-healing properties of polysaccharide-based self-healing hydrogels and its potential applications in biomedicine and other fields. [Display omitted]